Advair® Diskus®		Advair pricing
	Brand Advair manufactured by: GLAXOSMITHKLINE
	Chemical name: Salmeterol Xinafoate/Fluticasone Propionate (Generic not available)

	Advair® Inhaler Aerosol		Advair pricing
	Brand Advair manufactured by: GLAXOSMITHKLINE
	Chemical name: Salmeterol Xinafoate/Fluticasone Propionate (Generic not available)

Bronchodilator--Corticosteroid for Inhalation

IMPORTANT NOTE: The following information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

Advair Diskus (click here to skip down to Advair Aerosol Inhaler)

Advair Information | Advair Precautions | How To Take Advair | Advair Side Effects

Advair Diskus should be used only twice a day. Advair Diskus should not be used as relief medication.

The name of your medicine is Advair (salmeterol xinafoate/fluticasone propionate) Diskus.

Advair Diskus contains 2 active ingredients: salmeterol xinafoate and fluticasone propionate.

Advair Diskus Information: Salmeterol xinafoate is one of a group of medicines called bronchodilators. It relaxes the muscles in the walls of the small air passages in the lungs. This helps to open the airways and makes it easier for air to get in and out of the lungs. The effects of salmeterol xinafoate last for at least 12 hours. When it is taken regularly it helps the small air passages to remain open.

Fluticasone propionate is one of a group of medicines called corticosteroids. Corticosteroids are used to treat breathing problems because they have an anti-inflammatory action. They reduce the swelling and irritation in the walls of the small air passages in the lungs and so ease breathing problems. Corticosteroids also help to prevent attacks of asthma.

When you take these two ingredients together regularly, they will both help to control your breathing difficulties.

Your doctor has chosen this medicine to suit you and your condition. Advair Diskus is used to help with breathing problems in people who need regular treatment.

It is very important that you use your Advair Diskus every day, twice a day. This will help you to keep free of symptoms throughout the day and night.

Advair Diskus does not act quickly enough to be used as a relief medication. Advair Diskus should not be used to provide relief for a sudden attack of breathlessness. If you get a sudden attack of wheezing and breathlessness between your doses of Advair Diskus, you should take 1 or 2 puffs from a fast-acting relief medication (e.g., Ventolin) which your doctor has given you.

If you take more than 1 inhaled medicine, make sure you understand the purpose for taking each medication and when you should use them.

After you start taking Advair Diskus, your doctor may change the dosages of your other asthma medicines. Rarely, this may make a patient feel worse rather than better. This especially applies to oral corticosteroids (sometimes referred to as steroids), including prednisone. If your doctor decreases your oral steroid dose, and you become unwell, tell your doctor immediately.

Use in Asthma: Asthma is a chronic inflammatory disease of the lungs characterized by episodes of difficulty in breathing. People with asthma have extra-sensitive or “twitchy” airways. During an asthma attack, the airways react by narrowing, making it more difficult for the air to flow in and out of the lungs.

Control of asthma requires avoiding irritants that cause asthma attacks and taking the appropriate medications. For example, patients should avoid exposure to house dust mites, mold, pets, tobacco smoke and pollens.

The following warning signs indicate that your asthma is getting worse and that your treatment needs to be reassessed by your physician:

• A change in your symptoms such as more coughing, attacks of wheezing, chest tightness, or an unusual increase in the severity of the breathlessness.
• You wake up at night with chest tightness, wheezing or shortness of breath.
• You use increasing amounts of your fast-acting relief medication.
• Measurement from your peak flow meter indicates a value between 60 and 80% of predicted or personal best.

If you notice the following warning signs, you should contact your physician as soon as possible or go to the nearest hospital:

• A sudden worsening of your shortness of breath and wheezing shortly after using your fast-acting relief medication or after using Advair Diskus.
• You do not feel relief within 10 minutes after using your fast-acting medication or the relief does not last for at least 3 hours.
• Measurement from your peak flow meter indicates a value less than 60% of predicted or personal best.
• You are breathless at rest.
• Your pulse is more than 120 beats per minute.

Advair Precautions: Important Points to Note Before Taking Your Medicine:

• Have you ever had to stop taking another medication for your breathing problems because you were allergic to it or it caused problems?
• Have you been told you are allergic to lactose (milk sugar)?
• Have you ever had thrush in your mouth?
• Are you having treatment for a thyroid condition, diabetes, raised blood pressure, or heart problem?
• Do you have any history of tuberculosis (TB) infections?
• Are you taking other “steroids” by mouth or by inhalation?

If the answer is yes to any of these questions, tell your doctor or pharmacist as soon as possible if you have not already done so.

Make sure that your doctor knows what other medicines you are taking (such as those for allergies, nervousness, depression, migraine, etc.), including those you can buy without a prescription as well as herbal and alternative medicines.

Use of This Medicine During Pregnancy and Breast-feeding: Do not use this medication during pregnancy or breast-feeding without first discussing this with your doctor.

Taking Your Medicine (see package insert for illustrations): Follow the instructions shown. If you have any problems, tell your doctor or pharmacist.

It is important that you take each dose as instructed by your doctor, nurse, or pharmacist. Your doctor will decide which strength of Diskus you should use.

For patients 12 years of age and older, the usual dose is:

• 1 inhalation Advair 100 Diskus twice daily, or
• 1 inhalation Advair 250 Diskus twice daily, or
• 1 inhalation Advair 500 Diskus twice daily.

For children 4 to 11 years of age, the usual dose is 1 inhalation Advair 100 Diskus twice daily.

At present, there are insufficient clinical data to recommend the use of Advair Diskus in children younger than 4 years of age.

It is very important that you use Advair Diskus regularly every day. Do not stop treatment even if you feel better unless told to do so by your doctor.

Do not change your dose unless told to by your doctor.

If you are breathless or wheezing more often than normal, tell your doctor.

Advair Diskus should not be used more than twice daily.

How to Use Your Advair Diskus Inhalation Device Properly:
About your Diskus: Advair Diskus is available in 3 strengths:

Advair 100 Diskus is a plastic inhaler device containing a foil strip with 28 or 60 blisters. Each blister contains 50 µg of salmeterol (as the xinafoate salt) and 100 µg of fluticasone propionate as active ingredients. Also contains lactose which acts as a “carrier”.

Advair 250 Diskus is a plastic inhaler device containing a foil strip with 28 or 60 blisters. Each blister contains 50 µg of salmeterol (as the xinafoate salt) and 250 µg of fluticasone propionate as active ingredients. Also contains lactose which acts as a “carrier”.

Advair 500 Diskus is a plastic inhaler device containing a foil strip with 28 or 60 blisters. Each blister contains 50 µg of salmeterol (as the xinafoate salt) and 500 µg of fluticasone propionate as active ingredients. Also contains lactose which acts as a “carrier”.

The blisters protect the powder for inhalation from effects of the atmosphere.

When you take your Diskus out of its box, it will be in the closed position.

A new Diskus contains 28 or 60 individually protected doses of your medicine, in powder form. The device has a dose counter which tells you the number of doses remaining. It counts down from 28 or 60 to 1. To show when the last 5 doses have been reached, the numbers appear in red.

Each dose is accurately measured and hygienically protected. The Diskus requires no maintenance, and no refilling.

How Your Diskus Works: The Diskus is easy to use. When you need a dose, just follow the 4 simple steps illustrated:

1. Open   2. Slide   3. Inhale   4. Close

Sliding the lever of your Diskus opens a small hole in the mouthpiece and unwraps a dose ready for you to inhale it. When you close the Diskus, the lever automatically moves back to its original position ready for your next dose when you need it. The outer case protects your Diskus when it is not in use.

1. Open: To open your Diskus hold the outer case in one hand and put the thumb of your other hand on the thumb grip. Push your thumb away from you as far as it will go.

2. Slide: Hold your Diskus with the mouthpiece towards you. Slide the lever away from you as far as it will go--until it clicks. Your Diskus is now ready to use. Every time the lever is pushed back, a dose is made available for inhaling. This is shown by the dose counter. Do not play with the lever as this releases doses that will be wasted.

3.Inhale: Before you start to inhale the dose, read through this section carefully.

• Hold the Diskus away from your mouth. Breathe out as far as is comfortable. Remember, never breathe into your Diskus.
• Put the mouthpiece to your lips. Breathe in steadily and deeply--through the Diskus, not through your nose.
• Remove the Diskus from your mouth.
• Hold your breath for about 10 seconds or for as long as is comfortable.
• Breathe out slowly.

4. Close: To close your Diskus, put your thumb in the thumb grip, and slide the thumb grip back towards you, as far as it will go.

When you close the Diskus, it clicks shut. The lever automatically returns to its original position and is reset. Your Diskus is now ready for you to use again.

Remember: Keep your Diskus dry.

Keep it closed when not in use.

Never breathe into your Diskus. Only slide the lever when you are ready to take a dose.

After using your Advair Diskus Inhalation Device: If you notice a sudden worsening of your shortness of breath and wheeze shortly after using your Advair Diskus, tell your doctor as soon as possible.

Very occasionally some people feel a little shaky or have a headache or notice that their heart is beating faster than usual. These effects usually wear off with continued treatment. Tell your doctor but do not stop using the medicine unless told to do so.

Some people find that their mouth, throat or tongue becomes sore after taking this medicine or that their voice becomes a little hoarse. In some people, a mild yeast infection of the mouth and throat called candidiasis (thrush) may occur. Rinsing your mouth with water immediately after taking each dose may help. Do not swallow the water after rinsing. Tell your doctor but do not stop treatment unless told to do so.

Advair side effects: It is possible that some patients, especially those taking higher doses of this type of medication, may suffer from the following side effects: loss of bone density, eye problems and slowing of growth in children and adolescents. These effects are much less likely to occur than with steroid tablets. Studies have shown that children whose asthma is not controlled do not grow as quickly as other children. It is very important that you use your medicine regularly to control your asthma.

Medicines affect different people in different ways. Just because side effects have occurred in other patients does not mean you will get them. If any side effects bother you, please contact your doctor.

Some people can be allergic to medicines. If you have any of the following symptoms soon after taking Advair Diskus, stop taking this medicine and tell your doctor immediately.

• Sudden wheeziness and chest pain or tightness.
• Swelling of eyelids, face, lips, tongue or throat.
• Lumpy skin rash or “hives” anywhere on the body.

Also tell your doctor if you have any of the following symptoms: headache, muscle cramps, pains in joints, skin rash or trembling, increase in pulse rate, mouth or throat irritation.

If you feel unwell or have any symptoms that you do not understand, you should contact your doctor immediately.

If you take too much? If you accidentally take more than the recommended number of inhalations, you may notice that your heart is beating faster than usual, that you have a headache and that you feel shaky.

In this case, tell your doctor without delay or contact your hospital emergency department or nearest Poison Control Centre.

If you miss a dose? It is very important that you use Advair Diskus regularly; however, if you miss a single dose, do not worry--just take the next dose when it is due.

What to do if you stop your medicine? If your doctor decides to stop the treatment, do not keep any leftover medicine unless your doctor tells you to.

Storing Your Medicine: Keep your medicine in a safe place where children cannot reach it. Your medicine may harm them.

Do not store Advair Diskus above 30°C. Keep in a dry place.

Remember: This medicine is for you . Only a doctor can prescribe it for you. Never give it to someone else. It may harm them even if their symptoms are the same as yours.

If you have any questions or are not sure about anything to do with your medicine, then you should ask your doctor or the pharmacist.

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Advair Inhalation Aerosol:

Advair Information | Advair Precautions | How To Take Advair | Advair Side Effects

Please note that

indicates that this inhalation aerosol does not contain

Advair inhalation aerosol should be used only twice a day. Advair inhalation aerosol should NOT be used as relief medication.

The name of your medicine is Advair (salmeterol xinafoate/fluticasone propionate) inhalation aerosol.

Advair inhalation aerosol contains 2 active ingredients, salmeterol xinafoate and fluticasone propionate.

Advair Inhalation Aerosol Information: Salmeterol xinafoate is one of a group of medicines called bronchodilators. It relaxes the muscles in the walls of the small air passages in the lungs. This helps to open the airways and makes it easier for air to get in and out of the lungs. The effects of salmeterol xinafoate last for at least 12 hours. When it is taken regularly it helps the small air passages to remain open.

Fluticasone propionate is one of a group of medicines called corticosteroids. Corticosteroids are used to treat breathing problems because they have an anti-inflammatory action. They reduce the swelling and irritation in the walls of the small air passages in the lungs and so ease breathing problems. Corticosteroids also help to prevent attacks of asthma.

When you take these two ingredients together regularly they will both help to control your breathing difficulties.

Your doctor has chosen this medicine to suit you and your condition. Advair inhalation aerosol is used to help with breathing problems in people who need regular treatment.

It is very important that you use your Advair inhalation aerosol every day, twice a day. This will help you to keep free of symptoms throughout the day and night.

Advair inhalation aerosol does not act quickly enough to be used as a relief medication. Advair inhalation aerosol should not be used to provide relief for a sudden attack of breathlessness. If you get a sudden attack of wheezing and breathlessness between your doses of Advair inhalation aerosol, you should take 1 or 2 puffs from a fast-acting relief medication (e.g., Ventolin) which your doctor has given you.

If you take more than one inhaled medicine, make sure you understand the purpose for taking each medication and when you should use them.

After you start taking Advair inhalation aerosol, your doctor may change the dosages of your other asthma medicines. Rarely, this may make a patient feel worse rather than better. This especially applies to oral corticosteroids (sometimes referred to as steroids), including prednisone. If your doctor decreases your oral steroid dose, and you become unwell, tell your doctor immediately.

Use in Asthma: Asthma is a chronic inflammatory disease of the lungs characterized by episodes of difficulty in breathing. People with asthma have extrasensitive or “twitchy” airways. During an asthma attack, the airways react by narrowing, making it more difficult for the air to flow in and out of the lungs.

Control of asthma requires avoiding irritants that cause asthma attacks and taking the appropriate medications. For example, patients should avoid exposure to house dust mites, mold, pets, tobacco smoke and pollens.

The following warning signs indicate that your asthma is getting worse and that your treatment needs to be reassessed by your physician:

• change in your symptoms such as more coughing, attacks of wheezing, chest tightness, or an unusual increase in the severity of the breathlessness.
• You wake up at night with chest tightness, wheezing or shortness of breath.
• You use increasing amounts of your fast-acting relief medication.
• Measurement from your peak flow meter indicates a value between 60 and 80% of predicted or personal best.

If you notice the following warning signs, you should contact your physician as soon as possible or go to the nearest hospital:

• A sudden worsening of your shortness of breath and wheezing shortly after using your fast-acting relief medication or after using Advair inhalation aerosol.
• You do not feel relief within 10 minutes after using your fast-acting medication or the relief does not last for at least 3 hours.
• Measurement from your peak flow meter indicates a value less than 60 percent of predicted or personal best.
• You are breathless at rest.
• Your pulse is more than 120 beats per minute.

Advair Precautions: Important Points to Note Before Taking Your Medicine:

• Have you ever had to stop taking another medication for your breathing problems because you were allergic to it or it caused problems?
• Have you ever had thrush in your mouth?
• Are you having treatment for a thyroid condition, diabetes, raised blood pressure, or heart problem?
• Do you have any history of tuberculosis (TB) infections?
• Are you taking other “steroids” by mouth or by inhalation?

If the answer is yes to any of these questions, tell your doctor or pharmacist as soon as possible if you have not already done so.

Make sure that your doctor knows what other medicines you are taking (such as those for allergies, nervousness, depression, migraine, etc.), including those you can buy without a prescription as well as herbal and alternative medicines.

Use of This Medicine During Pregnancy and Breast-feeding: Do not use this medication during pregnancy or breast-feeding without first discussing this with your doctor.

Taking Your Medicine (see package insert for illustrations): Follow the instructions shown. If you have any problems, tell your doctor or pharmacist.

It is important that you take each dose as instructed by your doctor, nurse, or pharmacist. Your doctor will decide which strength of Advair inhalation aerosol you should use.

For patients 12 years of age and older, the usual dose is:

• Two inhalations Advair 125 inhalation aerosol twice daily, or
• Two inhalations Advair 250 inhalation aerosol twice daily.

At present, there are insufficient clinical data to recommend the use of Advair inhalation aerosol in children younger than 12 years of age.

It is very important that you use Advair inhalation aerosol regularly every day. Do not stop treatment even if you feel better unless told to do so by your doctor.

Do not change your dose unless told to by your doctor.

If you are breathless or wheezing more often than normal, tell your doctor.

Advair inhalation aerosol should not be used more than twice daily.

How to Use Your Advair Inhalation Aerosol Properly: Before you use your Advair inhalation aerosol for the first time, release 2 puffs into the air to ensure that it works properly, or if your inhaler has not been used for a week or more, release 1 puff into the air.

1. Remove the cap from the mouthpiece; the strap on the cap will stay attached to the actuator. Check the mouthpiece inside and outside to ensure that it is clean.

2. Shake the inhaler vigorously.

3. Hold the inhaler upright between fingers and thumb with your thumb on the base, below the mouthpiece. Breathe out as far as comfortable.

4. Place the mouthpiece in your mouth between your teeth and close your lips around it, but do not bite it. Just after starting to breathe in through your mouth, press down on the top of the inhaler to release the drug while still breathing in steadily and deeply.

5. While holding your breath, take the inhaler from your mouth and take your finger from the top of the inhaler. Continue holding your breath for about 10 seconds or for as long as is comfortable.

6. If you are to take further puffs, keep the inhaler upright and wait about half a minute before repeating steps 2 through 5.

7. After use, always snap the mouthpiece cover back into position to keep out dust and lint.

8. Rinse out your mouth with water after each dose. Do not swallow the water after rinsing.

Important: Do not rush stages 4 and 5. It is important that you start to breathe in as slowly as possible just before operating your inhaler. Practice in front of a mirror for the first few times. If you see “mist” coming from the top of your inhaler or the sides of your mouth, you should start again from stage 2.

If your doctor has given you different instructions for using your inhaler, please follow them carefully. Tell your doctor if you have any difficulties.

Children/Elderly: Some children may need help and an adult may need to operate the inhaler for them. Encourage the child to breathe out and operate the inhaler just after the child starts to breathe in. Practice the technique together. Children or people with weak hands should hold the inhaler with both hands. Put the two forefingers on top of the inhaler and both thumbs on the base below the mouthpiece.

Cleaning: Your inhaler should be cleaned at least once per week.

1. Pull the metal canister out of the plastic casing of the inhaler and remove the mouthpiece cover.

2. Wipe the plastic casing and mouthpiece cover with a damp cloth. Do not put the metal canister into water.

3. Leave the casing and mouthpiece cover to dry in a warm place. Avoid excessive heat.

4. Replace the canister and mouthpiece cover.

After Using Your Advair Inhalation Aerosol: If you notice a sudden worsening of your shortness of breath and wheeze shortly after using your Advair inhalation aerosol, tell your doctor as soon as possible.

Very occasionally some people feel a little shaky or have a headache or notice that their heart is beating faster than usual. These effects usually wear off with continued treatment. Tell your doctor but do not stop using the medicine unless told to do so.

Some people find that their throat or tongue becomes sore after taking this medicine or that their voice becomes a little hoarse. In some people, a mild yeast infection of the mouth and throat called candidiasis (thrush) may occur. Rinsing your mouth with water immediately after taking each dose may help. Do not swallow the water after rinsing. Tell your doctor but do not stop treatment unless told to do so.

Advair side effects: It is possible that some patients, especially those taking higher doses of this type of medication, may suffer from the following side effects: loss of bone density, eye problems and slowing of growth in children and adolescents. These effects are much less likely to occur than with steroid tablets. Studies have shown that children whose asthma is not controlled do not grow as quickly as other children. It is very important that you use your medicine regularly to control your asthma.

Medicines affect different people in different ways. Just because side effects have occurred in other patients does not mean you will get them. If any side effects bother you, please contact your doctor.

Some people can be allergic to medicines. If you have any of the following symptoms soon after taking Advair inhalation aerosol, stop taking this medicine and tell your doctor immediately.

• Sudden wheeziness and chest pain or tightness.
• Swelling of eyelids, face, lips, tongue or throat.
• Lumpy skin rash or “hives” anywhere on the body.

Also tell your doctor if you have any of the following symptoms: headache, muscle cramps, pains in joints, skin rash or trembling, increase in pulse rate, mouth or throat irritation.

If you feel unwell or have any symptoms that you do not understand, you should contact your doctor immediately.

If you take too much? If you accidentally take more than the recommended number of inhalations , you may notice that your heart is beating faster than usual, that you have a headache and that you feel shaky.

In this case, tell your doctor without delay or contact your hospital emergency department or nearest Poison Control Centre.

If you miss a dose? It is very important that you use Advair inhalation aerosol regularly; however, if you miss a single dose, do not worry--just take the next dose when it is due.

What to do if you stop your medicine? If your doctor decides to stop the treatment, do not keep any left-over medicine unless your doctor tells you to.

Storing Your Medicine:
Keep your medicine in a safe place where children cannot reach it. Your medicine may harm them.

Store Advair inhalation aerosol between 15 and 25°C. Protect from frost and direct sunlight.

As with most inhaled medications in pressurized canisters, the therapeutic effect of this medication may decrease when the canister is cold.

If the inhaler becomes very cold, remove the metal canister and warm in your hand for a few minutes. Never use other forms of heat.

Warning: The metal canister is pressurized. Do not puncture it or burn it, even when apparently empty.

Remember: This medicine is for you . Only a doctor can prescribe it for you. Never give it to someone else. It may harm them even if their symptoms are the same as yours.

If you have any questions or are not sure about anything to do with your medicine, then you should ask your doctor or the pharmacist.

Click Here to Buy Advair Inhalation Aerosol from our Affiliated Canadian Pharmacy Now

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